Zonisamide, an antiepileptic drug, alleviates diabetic cardiomyopathy by inhibiting endoplasmic reticulum stress

Endoplasmic reticulum stress (ER stress) plays a key role in the development of cardiac hypertrophy and diabetic cardiomyopathy (DCM). Zonisamide (ZNS) was originally developed as an antiepileptic drug. Studies have shown that ZNS suppresses ER stress-induced neuronal cell damage in the experimental...

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Bibliografiske detaljer
Udgivet i:Acta Pharmacol Sin
Main Authors: Tian, Jia-hui, Wu, Qian, He, Yong-xiang, Shen, Qi-ying, Rekep, Mubarak, Zhang, Gui-ping, Luo, Jian-dong, Xue, Qin, Liu, Ying-hua
Format: Artigo
Sprog:Inglês
Udgivet: Springer Singapore 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8026994/
https://ncbi.nlm.nih.gov/pubmed/32647341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41401-020-0461-z
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