Genomic alterations during the in situ to invasive ductal breast carcinoma transition shaped by the immune system

The drivers of ductal carcinoma in situ (DCIS) to invasive ductal carcinoma (IDC) transition are poorly understood. Here, we conducted an integrated genomic, transcriptomic, and whole-slide image analysis to evaluate changes in copy number profiles, mutational profiles, expression, neoantigen load a...

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Detalhes bibliográficos
Publicado no:Mol Cancer Res
Main Authors: Trinh, Anne, Gil Del Alcazar, Carlos R., Shukla, Sachet A., Chin, Koei, Chang, Young Hwan, Thibault, Guillaume, Eng, Jennifer, Jovanović, Bojana, Aldaz, C. Marcelo, Park, So Yeon, Jeong, Joon, Wu, Catherine, Gray, Joe, Polyak, Kornelia
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8026652/
https://ncbi.nlm.nih.gov/pubmed/33443130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-20-0949
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