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Widespread reorganisation of pluripotent factor binding and gene regulatory interactions between human pluripotent states

The transition from naive to primed pluripotency is accompanied by an extensive reorganisation of transcriptional and epigenetic programmes. However, the role of transcriptional enhancers and three-dimensional chromatin organisation in coordinating these developmental programmes remains incompletely...

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Publicado en:Nat Commun
Main Authors: Chovanec, Peter, Collier, Amanda J., Krueger, Christel, Várnai, Csilla, Semprich, Claudia I., Schoenfelder, Stefan, Corcoran, Anne E., Rugg-Gunn, Peter J.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2021
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8026613/
https://ncbi.nlm.nih.gov/pubmed/33828098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-22201-4
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