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Widespread reorganisation of pluripotent factor binding and gene regulatory interactions between human pluripotent states

The transition from naive to primed pluripotency is accompanied by an extensive reorganisation of transcriptional and epigenetic programmes. However, the role of transcriptional enhancers and three-dimensional chromatin organisation in coordinating these developmental programmes remains incompletely...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Chovanec, Peter, Collier, Amanda J., Krueger, Christel, Várnai, Csilla, Semprich, Claudia I., Schoenfelder, Stefan, Corcoran, Anne E., Rugg-Gunn, Peter J.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8026613/
https://ncbi.nlm.nih.gov/pubmed/33828098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-22201-4
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