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Genome Oligopaint via Local Denaturation Fluorescence in Situ Hybridization (GOLD FISH)
Cas9 in complex with a programmable guide RNA targets specific double-stranded DNA for cleavage. By harnessing Cas9 as a programmable loader of superhelicase to genomic DNA, here we report a physiological-temperature DNA FISH method termed Genome Oligopaint via Local Denaturation Fluorescence in Sit...
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| Publicado no: | Mol Cell |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8026568/ https://ncbi.nlm.nih.gov/pubmed/33657402 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2021.02.011 |
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