Single-molecule super-resolution imaging of chromosomes and in situ haplotype visualization using Oligopaint FISH probes

Fluorescence in situ hybridization (FISH) is a powerful single-cell technique for studying nuclear structure and organization. Here we report two advances in FISH-based imaging. We first describe the in situ visualization of single-copy regions of the genome using two single-molecule super-resolutio...

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Publicado no:Nat Commun
Main Authors: Beliveau, Brian J., Boettiger, Alistair N., Avendaño, Maier S., Jungmann, Ralf, McCole, Ruth B., Joyce, Eric F., Kim-Kiselak, Caroline, Bantignies, Frédéric, Fonseka, Chamith Y., Erceg, Jelena, Hannan, Mohammed A., Hoang, Hien G., Colognori, David, Lee, Jeannie T., Shih, William M., Yin, Peng, Zhuang, Xiaowei, Wu, Chao-ting
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Pub. Group 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4430122/
https://ncbi.nlm.nih.gov/pubmed/25962338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms8147
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