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Biomarkers of drug-induced liver injury: a mechanistic perspective through acetaminophen hepatotoxicity.

INTRODUCTION: Liver injury induced by drugs is a serious clinical problem. Many circulating biomarkers for identifying and predicting drug-induced liver injury (DILI) have been proposed. AREAS COVERED: Biomarkers are mainly predicated on the mechanistic understanding of the underlying DILI, often in...

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Detalhes bibliográficos
Publicado no:Expert Rev Gastroenterol Hepatol
Main Authors: Umbaugh, David S., Jaeschke, Hartmut
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8026489/
https://ncbi.nlm.nih.gov/pubmed/33242385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/17474124.2021.1857238
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