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Macrophage-derived PDGF-B induces muscularization in murine and human pulmonary hypertension
Excess macrophages and smooth muscle cells (SMCs) characterize many cardiovascular diseases, but crosstalk between these cell types is poorly defined. Pulmonary hypertension (PH) is a lethal disease in which lung arteriole SMCs proliferate and migrate, coating the normally unmuscularized distal arte...
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| Publicado no: | JCI Insight |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8026182/ https://ncbi.nlm.nih.gov/pubmed/33591958 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.139067 |
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