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IGF1R controls mechanosignaling in myofibroblasts required for pulmonary alveologenesis

Ventilation throughout life is dependent on the formation of pulmonary alveoli, which create an extensive surface area in which the close apposition of respiratory epithelium and endothelial cells of the pulmonary microvascular enables efficient gas exchange. Morphogenesis of the alveoli initiates a...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: He, Hua, Snowball, John, Sun, Fei, Na, Cheng-Lun, Whitsett, Jeffrey A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8026181/
https://ncbi.nlm.nih.gov/pubmed/33591952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.144863
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