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Hox5 genes direct elastin network formation during alveologenesis by regulating myofibroblast adhesion
Hox5 genes (Hoxa5, Hoxb5, Hoxc5) are exclusively expressed in the lung mesenchyme during embryogenesis, and the most severe phenotypes result from constitutive loss of function of all three genes. Because Hox5 triple null mutants exhibit perinatal lethality, the contribution of this paralogous group...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6233103/ https://ncbi.nlm.nih.gov/pubmed/30348760 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1807067115 |
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