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Deducing high-accuracy protein contact-maps from a triplet of coevolutionary matrices through deep residual convolutional networks

The topology of protein folds can be specified by the inter-residue contact-maps and accurate contact-map prediction can help ab initio structure folding. We developed TripletRes to deduce protein contact-maps from discretized distance profiles by end-to-end training of deep residual neural-networks...

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Detalhes bibliográficos
Publicado no:PLoS Comput Biol
Main Authors: Li, Yang, Zhang, Chengxin, Bell, Eric W., Zheng, Wei, Zhou, Xiaogen, Yu, Dong-Jun, Zhang, Yang
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8026059/
https://ncbi.nlm.nih.gov/pubmed/33770072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1008865
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