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Single Molecule Study of the Polymerization of RecA on dsDNA: The Dynamics of Individual Domains

In the Escherichia coli, RecA plays a central role in the recombination and repair of the DNA. For homologous recombination, RecA binds to ssDNA forming a nucleoprotein filament. The RecA-ssDNA filament searches for a homologous sequence on a dsDNA and, subsequently, RecA mediates strand exchange be...

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Bibliografiske detaljer
Udgivet i:Front Mol Biosci
Main Authors: Maman, Nitzan, Kumar, Pramod, Yadav, Amarjeet, Feingold, Mario
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8025788/
https://ncbi.nlm.nih.gov/pubmed/33842536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2021.609076
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