Down-regulation of cylindromatosis protein phosphorylation by BTK inhibitor promotes apoptosis of non-GCB-diffuse large B-cell lymphoma

BACKGROUND: Non-germinal center B-cell-like diffuse large B-cell lymphoma (non-GCB-DLBCL) has worse clinical outcome than GCB-DLBCL, and some relapsed/refractory non-GCB-DLBCL (R/R non-GCB-DLBCL) are even resistant to CD20 monoclonal antibody (rituximab). Bruton’s tyrosine kinase inhibitors (BTKis)...

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Vydáno v:Cancer Cell Int
Hlavní autoři: Xu, Xin, Wei, Ting, Zhong, Weijie, Ang, Rosalind, Lei, Ye, Zhang, Hui, Li, Qingshan
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2021
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Primary Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8025353/
https://ncbi.nlm.nih.gov/pubmed/33827598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-021-01891-2
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