Identification of BLNK and BTK as mediators of rituximab‐induced programmed cell death by CRISPR screens in GCB‐subtype diffuse large B‐cell lymphoma

Diffuse large B‐cell lymphoma (DLBCL) is characterized by extensive genetic heterogeneity, and this results in unpredictable responses to the current treatment, R‐CHOP, which consists of a cancer drug combination supplemented with the humanized CD20‐targeting monoclonal antibody rituximab. Despite i...

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Bibliographische Detailangaben
Veröffentlicht in:Mol Oncol
Hauptverfasser: Thomsen, Emil Aagaard, Rovsing, Anne Bruun, Anderson, Mads Valdemar, Due, Hanne, Huang, Jinrong, Luo, Yonglun, Dybkær, Karen, Mikkelsen, Jacob Giehm
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2020
Schlagworte:
Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7463323/
https://ncbi.nlm.nih.gov/pubmed/32585766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12753
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