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An Improved Process for the Palladium-Catalyzed C–O Cross-Coupling of Secondary Alcohols
An improved protocol for the Pd-catalyzed C–O cross-coupling of secondary alcohols is described. The use of biaryl phosphine L2 as the ligand was key to achieving efficient cross-coupling of (hetero)aryl chlorides with only a 20% molar excess of the alcohol. Additionally, we observed an unusual reac...
Gorde:
| Argitaratua izan da: | Org Lett |
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| Egile Nagusiak: | , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2020
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8025245/ https://ncbi.nlm.nih.gov/pubmed/32579375 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.0c01668 |
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