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Discovery of rare sulfated N-unsubstituted glucosamine based heparan sulfate analogs selectively activating chemokines
Achieving selective inhibition of chemokines with structurally well-defined heparan sulfate (HS) oligosaccharides can provide important insights into cancer cell migration and metastasis. However, HS is highly heterogeneous in chemical composition, which limits its therapeutic use. Here, we report t...
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| Veröffentlicht in: | Chem Sci |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Royal Society of Chemistry
2021
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8025211/ https://ncbi.nlm.nih.gov/pubmed/33889380 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0sc05862a |
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