Nicotinamide suppresses bevacizumab-induced epithelial-mesenchymal transition of ARPE-19 cells by attenuating oxidative stress

AIM: To investigate the effects of nicotinamide (NAM) on bevacizumab (BEV)-induced epithelial-mesenchymal transition (EMT) of human retinal pigment epithelial cells (ARPE-19) and the underling mechanisms. METHODS: ARPE-19 cells were treated with BEV for 24, 48, and 72h, and the variation degrees of...

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Bibliographische Detailangaben
Veröffentlicht in:Int J Ophthalmol
Hauptverfasser: Zhou, Li, Shi, De-Peng, Chu, Wen-Juan, Song, Shan, Hao, Xiang-Hui, Yang, Ling-Ling, Xu, Hai-Feng
Format: Artigo
Sprache:Inglês
Veröffentlicht: International Journal of Ophthalmology Press 2021
Schlagworte:
Basic Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8025166/
https://ncbi.nlm.nih.gov/pubmed/33875936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18240/ijo.2021.04.01
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