LncRNA SOX2‐OT regulates AKT/ERK and SOX2/GLI‐1 expression, hinders therapy, and worsens clinical prognosis in malignant lung diseases

The involvement of LncRNA SOX2‐overlapping transcript (SOX2‐OT), SOX2, and GLI‐1 transcription factors in cancer has been well documented. Nonetheless, it is still unknown whether co‐expressed SOX2‐OT/SOX2 or SOX2‐OT/SOX2/GLI‐1 axes are epigenetically/transcriptionally involved in terms of resistanc...

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Detalhes bibliográficos
Publicado no:Mol Oncol
Main Authors: Herrera‐Solorio, Abril Marcela, Peralta‐Arrieta, Irlanda, Armas López, Leonel, Hernández‐Cigala, Nallely, Mendoza Milla, Criselda, Ortiz Quintero, Blanca, Catalán Cárdenas, Rodrigo, Pineda Villegas, Priscila, Rodríguez Villanueva, Evelyn, Trejo Iriarte, Cynthia G., Zúñiga, Joaquín, Arrieta, Oscar, Ávila‐Moreno, Federico
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8024737/
https://ncbi.nlm.nih.gov/pubmed/33433063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12875
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