Targeted inhibition of ERα signaling and PIP5K1α/Akt pathways in castration‐resistant prostate cancer

Selective ERα modulator, tamoxifen, is well tolerated in a heavily pretreated castration‐resistant prostate cancer (PCa) patient cohort. However, its targeted gene network and whether expression of intratumor ERα due to androgen deprivation therapy (ADT) may play a role in PCa progression is unknown...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Mol Oncol
Prif Awduron: Semenas, Julius, Wang, Tianyan, Sajid Syed Khaja, Azharuddin, Firoj Mahmud, AKM, Simoulis, Athanasios, Grundström, Thomas, Fällman, Maria, Persson, Jenny L.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: John Wiley and Sons Inc. 2020
Pynciau:
Research Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC8024724/
https://ncbi.nlm.nih.gov/pubmed/33275817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12873
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