Genomic and prognostic heterogeneity among RAS/BRAF (V600E)/TP53 co‐mutated resectable colorectal liver metastases

Hepatic resection is potentially curative for patients with colorectal liver metastases, but the treatment benefit varies. KRAS/NRAS (RAS)/TP53 co‐mutations are associated with a poor prognosis after resection, but there is large variation in patient outcome within the mutation groups, and genetic t...

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Dades bibliogràfiques
Publicat a:Mol Oncol
Autors principals: Berg, Kaja C. G., Brunsell, Tuva H., Sveen, Anita, Alagaratnam, Sharmini, Bjørnslett, Merete, Hektoen, Merete, Brudvik, Kristoffer W., Røsok, Bård I., Bjørnbeth, Bjørn Atle, Nesbakken, Arild, Lothe, Ragnhild A.
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2021
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8024718/
https://ncbi.nlm.nih.gov/pubmed/33325154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12885
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