Gene expression profiles of CMS2-epithelial/canonical colorectal cancers are largely driven by DNA copy number gains

About 80% of colorectal cancers (CRCs) have chromosomal instability, which is an integral part of aggressive malignancy development, but the importance of specific copy number aberrations (CNAs) in modulating gene expression, particularly within the framework of clinically relevant molecular subtype...

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Bibliografski detalji
Izdano u:Oncogene
Glavni autori: Berg, Kaja C. G., Sveen, Anita, Høland, Maren, Alagaratnam, Sharmini, Berg, Marianne, Danielsen, Stine A., Nesbakken, Arild, Søreide, Kjetil, Lothe, Ragnhild A.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2019
Teme:
Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6756070/
https://ncbi.nlm.nih.gov/pubmed/31308487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-019-0868-5
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