Gene expression profiles of CMS2-epithelial/canonical colorectal cancers are largely driven by DNA copy number gains

About 80% of colorectal cancers (CRCs) have chromosomal instability, which is an integral part of aggressive malignancy development, but the importance of specific copy number aberrations (CNAs) in modulating gene expression, particularly within the framework of clinically relevant molecular subtype...

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Detalhes bibliográficos
Publicado no:Oncogene
Main Authors: Berg, Kaja C. G., Sveen, Anita, Høland, Maren, Alagaratnam, Sharmini, Berg, Marianne, Danielsen, Stine A., Nesbakken, Arild, Søreide, Kjetil, Lothe, Ragnhild A.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6756070/
https://ncbi.nlm.nih.gov/pubmed/31308487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-019-0868-5
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