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Voltage Gated Sodium Channel Genes in Epilepsy: Mutations, Functional Studies, and Treatment Dimensions

Genetic epilepsy occurs as a result of mutations in either a single gene or an interplay of different genes. These mutations have been detected in ion channel and non-ion channel genes. A noteworthy class of ion channel genes are the voltage gated sodium channels (VGSCs) that play key roles in the d...

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Pubblicato in:Front Neurol
Autori principali: Ademuwagun, Ibitayo Abigail, Rotimi, Solomon Oladapo, Syrbe, Steffen, Ajamma, Yvonne Ukamaka, Adebiyi, Ezekiel
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8024648/
https://ncbi.nlm.nih.gov/pubmed/33841294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fneur.2021.600050
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