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Normal tissue architecture determines the evolutionary course of cancer

Cancer growth can be described as a caricature of the renewal process of the tissue of origin, where the tissue architecture has a strong influence on the evolutionary dynamics within the tumor. Using a classic, well-studied model of tumor evolution (a passenger-driver mutation model) we systematica...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: West, Jeffrey, Schenck, Ryan O., Gatenbee, Chandler, Robertson-Tessi, Mark, Anderson, Alexander R. A.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8024392/
https://ncbi.nlm.nih.gov/pubmed/33824323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-22123-1
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