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CAR-T cell therapy: current limitations and potential strategies

Chimeric antigen receptor (CAR)-T cell therapy is a revolutionary new pillar in cancer treatment. Although treatment with CAR-T cells has produced remarkable clinical responses with certain subsets of B cell leukemia or lymphoma, many challenges limit the therapeutic efficacy of CAR-T cells in solid...

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Pubblicato in:Blood Cancer J
Autori principali: Sterner, Robert C., Sterner, Rosalie M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8024391/
https://ncbi.nlm.nih.gov/pubmed/33824268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41408-021-00459-7
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