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Somatic CG6015 mediates cyst stem cell maintenance and germline stem cell differentiation via EGFR signaling in Drosophila testes

Stem cell niche is regulated by intrinsic and extrinsic factors. In the Drosophila testis, cyst stem cells (CySCs) support the differentiation of germline stem cells (GSCs). However, the underlying mechanisms remain unclear. In this study, we found that somatic CG6015 is required for CySC maintenanc...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Cell Death Discov
Hauptverfasser: Zheng, Qianwen, Chen, Xia, Qiao, Chen, Wang, Min, Chen, Wanyin, Luan, Xiaojin, Yan, Yidan, Shen, Cong, Fang, Jie, Hu, Xing, Zheng, Bo, Wu, Yibo, Yu, Jun
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8024382/
https://ncbi.nlm.nih.gov/pubmed/33824283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41420-021-00452-w
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