Somatic CG6015 mediates cyst stem cell maintenance and germline stem cell differentiation via EGFR signaling in Drosophila testes

Stem cell niche is regulated by intrinsic and extrinsic factors. In the Drosophila testis, cyst stem cells (CySCs) support the differentiation of germline stem cells (GSCs). However, the underlying mechanisms remain unclear. In this study, we found that somatic CG6015 is required for CySC maintenanc...

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Bibliografiske detaljer
Udgivet i:Cell Death Discov
Main Authors: Zheng, Qianwen, Chen, Xia, Qiao, Chen, Wang, Min, Chen, Wanyin, Luan, Xiaojin, Yan, Yidan, Shen, Cong, Fang, Jie, Hu, Xing, Zheng, Bo, Wu, Yibo, Yu, Jun
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8024382/
https://ncbi.nlm.nih.gov/pubmed/33824283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41420-021-00452-w
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