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Membrane lymphotoxin-α(2)β is a novel tumor necrosis factor (TNF) receptor 2 (TNFR2) agonist

In the early 1990s, it has been described that LTα and LTβ form LTα(2)β and LTαβ(2) heterotrimers, which bind to TNFR1 and LTβR, respectively. Afterwards, the LTαβ(2)–LTβR system has been intensively studied while the LTα(2)β–TNFR1 interaction has been ignored to date, presumably due to the fact tha...

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Dades bibliogràfiques
Publicat a:Cell Death Dis
Autors principals: Kucka, Kirstin, Lang, Isabell, Zhang, Tengyu, Siegmund, Daniela, Medler, Juliane, Wajant, Harald
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8024344/
https://ncbi.nlm.nih.gov/pubmed/33824270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-021-03633-8
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