LncRNA-HOTAIR activates autophagy and promotes the imatinib resistance of gastrointestinal stromal tumor cells through a mechanism involving the miR-130a/ATG2B pathway

Gastrointestinal stromal tumors (GISTs) are common neoplasms of the gastrointestinal tract that can be treated successfully using C-kit target therapy and surgery; however, imatinib chemoresistance is a major barrier to success in therapy. The present study aimed to discover alternative pathways in...

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Publicat a:Cell Death Dis
Autors principals: Zhang, Jinyan, Chen, Ke, Tang, Yuexiao, Luan, Xiaorui, Zheng, Xiaoxiao, Lu, Xuemei, Mao, Jiayan, Hu, Liqiang, Zhang, Shufen, Zhang, Xianning, Chen, Wei
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2021
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8024283/
https://ncbi.nlm.nih.gov/pubmed/33824300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-021-03650-7
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