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Effects of pH on an IDP conformational Ensemble Explored by Molecular Dynamics Simulation

The conformational ensemble of intrinsically disordered proteins, such as α-synuclein, are responsible for their function and malfunction. Misfolding of α-synuclein can lead to neurodegenerative diseases, and the ability to study their conformations and those of other intrinsically disordered protei...

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Detalhes bibliográficos
Publicado no:Biophys Chem
Main Authors: Lindsay, Richard J., Mansbach, Rachael A., Gnanakaran, S., Shen, Tongye
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8024028/
https://ncbi.nlm.nih.gov/pubmed/33581430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpc.2021.106552
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