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Simplified MethylRAD Sequencing to Detect Changes in DNA Methylation at Enhancer Elements in Differentiating Embryonic Stem Cells

Differential DNA methylation is characteristic of gene regulatory regions, such as enhancers, which mostly constitute low or intermediate CpG content in their DNA sequence. Consequently, quantification of changes in DNA methylation at these sites is challenging. Given that DNA methylation across mos...

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Bibliographische Detailangaben
Veröffentlicht in:Epigenomes
Hauptverfasser: Saha, Debapriya, Norvil, Allison B., Lanman, Nadia A., Gowher, Humaira
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8023688/
https://ncbi.nlm.nih.gov/pubmed/33828860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/epigenomes4040024
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