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ClonoMatch: a tool for identifying homologous immunoglobulin and T-cell receptor sequences in large databases

SUMMARY: B-cell receptor (BCR) and T-cell receptor (TCR) repertoires are generated through somatic DNA rearrangements and are responsible for the molecular basis of antigen recognition in the immune system. Next-generation sequencing (NGS) of DNA and the falling cost of sequencing due to continued d...

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Bibliographic Details
Published in:Bioinformatics
Main Authors: Jones, Taylor, Day, Samuel B, Myers, Luke, Crowe, James E, Soto, Cinque
Format: Artigo
Language:Inglês
Published: Oxford University Press 2020
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8023686/
https://ncbi.nlm.nih.gov/pubmed/33325481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btaa1028
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