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A non-linear regression method for estimation of gene–environment heritability

MOTIVATION: Gene–environment (GxE) interactions are one of the least studied aspects of the genetic architecture of human traits and diseases. The environment of an individual is inherently high dimensional, evolves through time and can be expensive and time consuming to measure. The UK Biobank stud...

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Pubblicato in:Bioinformatics
Autori principali: Kerin, Matthew, Marchini, Jonathan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8023682/
https://ncbi.nlm.nih.gov/pubmed/33367483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btaa1079
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