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Efficient Amino Acid Conformer Search with Bayesian Optimization

[Image: see text] Finding low-energy molecular conformers is challenging due to the high dimensionality of the search space and the computational cost of accurate quantum chemical methods for determining conformer structures and energies. Here, we combine active-learning Bayesian optimization (BO) a...

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Detalhes bibliográficos
Publicado no:J Chem Theory Comput
Main Authors: Fang, Lincan, Makkonen, Esko, Todorović, Milica, Rinke, Patrick, Chen, Xi
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2021
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8023666/
https://ncbi.nlm.nih.gov/pubmed/33577313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jctc.0c00648
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