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Efficient Amino Acid Conformer Search with Bayesian Optimization

[Image: see text] Finding low-energy molecular conformers is challenging due to the high dimensionality of the search space and the computational cost of accurate quantum chemical methods for determining conformer structures and energies. Here, we combine active-learning Bayesian optimization (BO) a...

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Vydáno v:J Chem Theory Comput
Hlavní autoři: Fang, Lincan, Makkonen, Esko, Todorović, Milica, Rinke, Patrick, Chen, Xi
Médium: Artigo
Jazyk:Inglês
Vydáno: American Chemical Society 2021
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8023666/
https://ncbi.nlm.nih.gov/pubmed/33577313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jctc.0c00648
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