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License to kill: microsatellite instability and immune contexture
Colorectal cancers (CRCs) with microsatellite instability (MSI) are due to a defect in the DNA mismatch repair (MMR) system resulting in an accumulation of frame-shift mutations. They are characterized by a tumor microenvironment richer in cytotoxic CD8 T-cells (CTLs) and a better prognosis compared...
Gardado en:
| Publicado en: | Oncoimmunology |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Taylor & Francis
2021
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8023238/ https://ncbi.nlm.nih.gov/pubmed/33868790 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2021.1905935 |
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