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LI Detector: a framework for sensitive colony-based screens regardless of the distribution of fitness effects
Microbial growth characteristics have long been used to investigate fundamental questions of biology. Colony-based high-throughput screens enable parallel fitness estimation of thousands of individual strains using colony growth as a proxy for fitness. However, fitness estimation is complicated by s...
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| Izdano u: | G3 (Bethesda) |
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| Glavni autori: | , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Oxford University Press
2021
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8022918/ https://ncbi.nlm.nih.gov/pubmed/33693606 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/g3journal/jkaa068 |
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