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A Photoswitchable Inhibitor of the Human Serotonin Transporter

The human serotonin transporter (hSERT) terminates serotonergic signaling through reuptake of neurotransmitter into presynaptic neurons and is a target for many antidepressant drugs. We describe here the development of a photoswitchable hSERT inhibitor, termed azo-escitalopram, that can be reversibl...

詳細記述

保存先:
書誌詳細
出版年:ACS Chem Neurosci
主要な著者: Cheng, Bichu, Morstein, Johannes, Ladefoged, Lucy Kate, Maesen, Jannick Bang, Schiøtt, Birgit, Sinning, Steffen, Trauner, Dirk
フォーマット: Artigo
言語:Inglês
出版事項: 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC8022892/
https://ncbi.nlm.nih.gov/pubmed/32275382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschemneuro.9b00521
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