Exosomes derived from miR-26a-modified MSCs promote axonal regeneration via the PTEN/AKT/mTOR pathway following spinal cord injury

BACKGROUND: Exosomes derived from the bone marrow mesenchymal stem cell (MSC) have shown great potential in spinal cord injury (SCI) treatment. This research was designed to investigate the therapeutic effects of miR-26a-modified MSC-derived exosomes (Exos-26a) following SCI. METHODS: Bioinformatics...

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Detalhes bibliográficos
Publicado no:Stem Cell Res Ther
Main Authors: Chen, Yuyong, Tian, Zhenming, He, Lei, Liu, Can, Wang, Nangxiang, Rong, Limin, Liu, Bin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8022427/
https://ncbi.nlm.nih.gov/pubmed/33820561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-021-02282-0
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