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Vitamin D receptor upregulates lncRNA TOPORS-AS1 which inhibits the Wnt/β-catenin pathway and associates with favorable prognosis of ovarian cancer

Long non-coding RNAs (lncRNAs) have important biological functions, but their involvement in ovarian cancer remains elusive. We analyzed high-throughput data to identify lncRNAs associated with ovarian cancer outcomes. Our search led to the discovery of lncRNA TOPORS Antisense RNA 1 (TOPORS-AS1). Pa...

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Foilsithe in:Sci Rep
Main Authors: Fu, Yuanyuan, Katsaros, Dionyssios, Biglia, Nicoletta, Wang, Zhanwei, Pagano, Ian, Tius, Marcus, Tiirikainen, Maarit, Rosser, Charles, Yang, Haining, Yu, Herbert
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group UK 2021
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8021562/
https://ncbi.nlm.nih.gov/pubmed/33820921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-86923-7
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