Low expression of WWC1, a tumor suppressor gene, is associated with aggressive breast cancer and poor survival outcome

The WW and C2 domain containing 1 (WWC1) gene encodes a protein named WWC1 (or KIBRA), which is involved in the Hippo signaling pathway. WWC1 is often lost in triple‐negative breast cancer and has been shown to suppress tumor metastasis. In this study, 470 breast cancer patients were recruited and W...

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Veröffentlicht in:FEBS Open Bio
Hauptverfasser: Wang, Zhanwei, Katsaros, Dionyssios, Biglia, Nicoletta, Shen, Yi, Fu, Yuanyuan, Tiirikainen, Maarit, Yu, Herbert
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2019
Schlagworte:
Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6609559/
https://ncbi.nlm.nih.gov/pubmed/31102318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/2211-5463.12659
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