Low expression of WWC1, a tumor suppressor gene, is associated with aggressive breast cancer and poor survival outcome

The WW and C2 domain containing 1 (WWC1) gene encodes a protein named WWC1 (or KIBRA), which is involved in the Hippo signaling pathway. WWC1 is often lost in triple‐negative breast cancer and has been shown to suppress tumor metastasis. In this study, 470 breast cancer patients were recruited and W...

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Publicat a:FEBS Open Bio
Autors principals: Wang, Zhanwei, Katsaros, Dionyssios, Biglia, Nicoletta, Shen, Yi, Fu, Yuanyuan, Tiirikainen, Maarit, Yu, Herbert
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2019
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6609559/
https://ncbi.nlm.nih.gov/pubmed/31102318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/2211-5463.12659
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