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Hormonal Modulation of ESR1 Mutant Metastasis
Estrogen receptor alpha gene (ESR1) mutations occur frequently in ER-positive metastatic breast cancer (MBC), and confer clinical resistance to aromatase inhibitors (AIs). Expression of the ESR1 Y537S mutation induced an epithelial-mesenchymal transition (EMT) with cells exhibiting enhanced migratio...
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| I publikationen: | Oncogene |
|---|---|
| Huvudupphovsmän: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
2020
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8020875/ https://ncbi.nlm.nih.gov/pubmed/33323970 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-020-01563-x |
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