Estrogen receptor β and treatment with a phytoestrogen are associated with inhibition of nuclear translocation of EGFR in the prostate

Knockout of ERβ in the mouse leads to nuclear expression of epidermal growth factor receptor (EGFR) in the prostate. To examine whether ERβ plays a similar role in the human prostate, we used four cohorts of men: 1) a Swedish cohort of normal prostates and PCa (prostate cancer) of different Gleason...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Wu, Wan-fu, Wang, Li, Spetsieris, Nicholas, Boukovala, Myrto, Efstathiou, Eleni, Brössner, Clemens, Warner, Margaret, Gustafsson, Jan-Ake
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2021
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8020780/
https://ncbi.nlm.nih.gov/pubmed/33771918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2011269118
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