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Estrogen receptor β and treatment with a phytoestrogen are associated with inhibition of nuclear translocation of EGFR in the prostate

Knockout of ERβ in the mouse leads to nuclear expression of epidermal growth factor receptor (EGFR) in the prostate. To examine whether ERβ plays a similar role in the human prostate, we used four cohorts of men: 1) a Swedish cohort of normal prostates and PCa (prostate cancer) of different Gleason...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Wu, Wan-fu, Wang, Li, Spetsieris, Nicholas, Boukovala, Myrto, Efstathiou, Eleni, Brössner, Clemens, Warner, Margaret, Gustafsson, Jan-Ake
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2021
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8020780/
https://ncbi.nlm.nih.gov/pubmed/33771918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2011269118
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