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Estrogen receptor β and treatment with a phytoestrogen are associated with inhibition of nuclear translocation of EGFR in the prostate

Knockout of ERβ in the mouse leads to nuclear expression of epidermal growth factor receptor (EGFR) in the prostate. To examine whether ERβ plays a similar role in the human prostate, we used four cohorts of men: 1) a Swedish cohort of normal prostates and PCa (prostate cancer) of different Gleason...

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Podrobná bibliografie
Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Wu, Wan-fu, Wang, Li, Spetsieris, Nicholas, Boukovala, Myrto, Efstathiou, Eleni, Brössner, Clemens, Warner, Margaret, Gustafsson, Jan-Ake
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8020780/
https://ncbi.nlm.nih.gov/pubmed/33771918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2011269118
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