Restoration of NK Cell Cytotoxic Function With Elotuzumab and Daratumumab Promotes Elimination of Circulating Plasma Cells in Patients With SLE

Systemic lupus erythematosus (SLE) is a multisystem autoimmune disease characterized by multiple cellular and molecular dysfunctions of the innate and adaptive immunity. Cytotoxic function of NK cells is compromised in patients with SLE. Herein, we characterized the phenotypic alterations of SLE NK...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Humbel, Morgane, Bellanger, Florence, Fluder, Natalia, Horisberger, Alice, Suffiotti, Madeleine, Fenwick, Craig, Ribi, Camillo, Comte, Denis
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8019934/
https://ncbi.nlm.nih.gov/pubmed/33828555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.645478
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