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Gut-Derived Metabolite Indole-3-Propionic Acid Modulates Mitochondrial Function in Cardiomyocytes and Alters Cardiac Function

Background: The gut microbiome has been linked to the onset of cardiometabolic diseases, in part facilitated through gut microbiota-dependent metabolites such as trimethylamine-N-oxide. However, molecular pathways associated to heart failure mediated by microbial metabolites remain largely elusive....

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Foilsithe in:Front Med (Lausanne)
Main Authors: Gesper, Maren, Nonnast, Alena B. H., Kumowski, Nina, Stoehr, Robert, Schuett, Katharina, Marx, Nikolaus, Kappel, Ben A.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Frontiers Media S.A. 2021
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8019752/
https://ncbi.nlm.nih.gov/pubmed/33829028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmed.2021.648259
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