Metformin prevents stroke damage in non-diabetic female mice with chronic kidney disease

Chronic kidney disease (CKD) worsens ischemic stroke severity in both patients and animals. In mice, these poorer functional outcomes are associated with decreased brain activity of AMP-activated protein kinase (AMPK), a molecule that recently emerged as a potential therapeutic target for ischemic s...

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Publicado en:Sci Rep
Main Authors: Grissi, Maria, Boudot, Cédric, Assem, Maryam, Candellier, Alexandre, Lando, Mathilde, Poirot-Leclercq, Sabrina, Boullier, Agnès, Bennis, Youssef, Lenglet, Gaëlle, Avondo, Carine, Lalau, Jean-Daniel, Choukroun, Gabriel, Massy, Ziad A., Kamel, Saïd, Chillon, Jean-Marc, Hénaut, Lucie
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2021
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8018962/
https://ncbi.nlm.nih.gov/pubmed/33811249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-86905-9
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