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Metformin prevents stroke damage in non-diabetic female mice with chronic kidney disease
Chronic kidney disease (CKD) worsens ischemic stroke severity in both patients and animals. In mice, these poorer functional outcomes are associated with decreased brain activity of AMP-activated protein kinase (AMPK), a molecule that recently emerged as a potential therapeutic target for ischemic s...
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| Udgivet i: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group UK
2021
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8018962/ https://ncbi.nlm.nih.gov/pubmed/33811249 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-86905-9 |
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