Gemfibrozil Protects Dopaminergic Neurons in a Mouse Model of Parkinson's Disease via PPARα-Dependent Astrocytic GDNF Pathway

Parkinson's disease (PD) is the most common neurodegenerative movement disorder in humans. Despite intense investigations, effective therapies are not yet available to halt the progression of PD. Gemfibrozil, a Food and Drug Administration-approved lipid-lowering drug, is known to decrease the...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Gottschalk, Carl G., Jana, Malabendu, Roy, Avik, Patel, Dhruv R., Pahan, Kalipada
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2021
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8018777/
https://ncbi.nlm.nih.gov/pubmed/33514677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3018-19.2021
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