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Rapid Aging in the Perforant Path Projections to the Rodent Dentate Gyrus

Why layers II/III of entorhinal cortex (EC) deteriorate in advance of other regions during the earliest stages of Alzheimer's disease is poorly understood. Failure of retrograde trophic support from synapses to cell bodies is a common cause of neuronal atrophy, and we accordingly tested for ear...

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Publicat a:J Neurosci
Autors principals: Amani, Mohammad, Lauterborn, Julie C., Le, Aliza A., Cox, Brittney M., Wang, Weisheng, Quintanilla, Julian, Cox, Conor D., Gall, Christine M., Lynch, Gary
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8018768/
https://ncbi.nlm.nih.gov/pubmed/33514675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2376-20.2021
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